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Tag Archives: Troy MI Root Canal

Tobacco Use and Alcohol Intake Key Risk Factors for Head and Neck Cancer

head and neck cancer
head and neck cancerThis type of cancer can be found early by your dental provider, so it just makes sense that they can help with prevention as well! Read the study below and thank you for visiting Personal Endodontics of Troy, MI!

Worldwide it is estimated that there were around 600,000 cases and 325,000 deaths from head and neck cancer in 2012. Tobaccos and alcohol well established risk factors and are though to account for about 75% of head and neck cancers. The International Head and Neck Cancer Epidemiology (INHANCE) Consortium was established in 2004 to help clarify the role of lifestyle factors and investigate other aetiologic questions.

The aim of this overview paper was to summarise the findings of the INHANCE consortium to date.


The INHANCE consortium includes investigators of 35 studies who have pooled their data on 25,500 patients with head and neck cancer (i.e., cancers of the oral cavity, oro- pharynx, hypopharynx, and larynx) and 37,100 controls. Cases are included in the INHANCE consortium if their tumor had been classified by the original study as an invasive tumor of oral cavity, oropharynx, hypopharynx, oral cavity or pharynx not otherwise specified, larynx, or head and neck cancer unspecified according to the International Classification of Diseases for Oncology, version 2 [ICD- O-2], or the International Classification of Diseases, 9th [ICD-9; (30)] or 10th [ICD-10] Revision.

Most are case–control studies involving patients with head and neck cancer and a comparison group of controls without head and neck cancer; the other studies are case series-patients with head and neck cancers.

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How Bioceramics Could Help Fight Gum Disease

gum disease
gum diseaseResearchers continue to look for better ways to treat and prevent gum disease. Read the promising results of a new study below and thank you for visiting Personal Endodontics of Troy, MI!

Severe gum disease known as periodontitis can lead to tooth loss, and treating it remains a challenge. But new approaches involving silicon nitride, a ceramic material used in spinal implants, could be on the way. The surface of silicon nitride has a lethal effect on the bacteria that commonly cause periodontitis. Now scientists, reporting in ACS’ journalLangmuir, are examining why this happens. Their findings could help inform future efforts to treat the disease.

About half of American adults have some form of gum disease. It’s caused by bacteria that infect the tissue around teeth, resulting in gum inflammation. If the condition progresses, the bacteria can damage the bone that supports the teeth. In addition to tooth loss, periodontitis can increase a person’s risk of heart attack or stroke. Options for treatment include scaling and root planing, topical antibiotics and surgery. Giuseppe Pezzotti and colleagues wanted to find a new alternative by studying the reactions of bacteria to antimicrobial silicon nitride.

The researchers investigated how the ceramic material changes the metabolism of Porphyromonas gingivalis — the bacteria species primarily responsible for periodontitis. They found that chemical reactions at the surface cause the bacteria’s nucleic acids to degrade and drastically reduce the amounts of certain proteins and fats. While further studies are needed, the results show silicon nitride holds promise as a therapeutic aid for treating severe gum disease.

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Signs of Naturally Occurring Chronic Periodontitis Reversed

periodontitisExciting new treatment in the works for periodontitis! Read more below and thank you for visiting Personal Endodontics of Troy, MI!

Periodontitis, a gum disease present in nearly half of all adults in the United States, involves inflammation, bleeding and bone loss. In its severe form, it is associated with systemic inflammatory conditions such as atherosclerosis and rheumatoid arthritis. Few treatment options exist beyond dental scaling and root planing, done in an attempt to reduce plaque and inflammation.

Now, with findings from a study led by University of Pennsylvania researchers, there is new hope that the disease can be effectively reversed.

The work, which appears in the Journal of Clinical Periodontology, employed an inhibitor of a protein called C3, a component of the body’s complement system, which is involved in immunity and inflammatory responses. Delivering this inhibitor, Cp40, to the periodontal tissue just once a week reversed naturally occurring chronic periodontitis inflammation in a preclinical model.

George Hajishengallis, Thomas W. Evans Centennial Professor inPenn’s School of Dental Medicine’s Department of Biology, and John D. Lambris, Dr. Ralph and Sallie Weaver Professor of Research Medicine in the Perelman School of Medicine’s Department of Pathology and Laboratory Medicine, were co-senior authors on the study, the result of years of collaboration.

“Even after one treatment, you could see a big difference in inflammation,” said Hajishengallis. “After six weeks, we saw reversals in inflammation, both clinically and by looking at cellular and molecular measures of osteoclast formation and inflammatory cytokines.”

“The results were so clean, so impressive,” Lambris said. “The next step is to pursue Phase 1 trials in humans.”

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Does Sleep Disordered Breathing Influence Facial Form

sleep disordered breathing
Are you a mouth breather? Is your child? If so, you may want to read on and thank you for visiting Personal Endodontics of Troy, MI!

One of the most controversial areas in orthodontics is the relationship between craniofacial form and breathing. This is very relevant because we do not know how much the environment (e.g. breathing) influences the aetiology of malocclusion. This area of research is becoming increasingly important as we search for treatments that correct functional problems. This recent, open access, paper sheds some light on this interesting area.

One of the lead investigators is Prof Stephen Richmond from Cardiff University, Wales. I had the pleasure of working with him in Manchester from 1984 – 1993. His major work has been in the development of measures and he has refined the index of orthodontic treatment need and invented the PAR index. I shared an office with him for several years and his area of our office was always covered in piles of dental casts, papers and measuring devices, while mine had a completely clear desk. I still miss those vibrant days, but I do not miss the untidy office!,

In this paper, they investigated the relationship between the prevalence of sleep disordered breathing (SDB) and face shape in a large sample of 15-year-old young people. They wanted to investigate this problem because SDB is a subtle disorder of childhood and it may have serious consequences. The prevalence varies between 2 to 16%. They provided an excellent literature which covered the subject very well and this is well worth reading.

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Periodontal Disease Associated with Increased Breast Cancer Risk in Postmenopausal Women

head and neck cancer
breast cancerThis is disturbing! Please read and thank you for visiting Personal Endodontics of Troy, MI!

Periodontal disease is a common condition that has been associated with heart disease, stroke, and diabetes. Previous research has found links between periodontal disease and oral, esophageal, head and neck, pancreatic, and lung cancers, so the researchers wanted to see if there was any relationship with breast cancer.

Jo L. Freudenheim, PhD, and colleagues monitored 73,737 postmenopausal women enrolled in the Women’s Health Initiative Observational Study, none of whom had previous breast cancer. Periodontal disease was reported in 26.1 percent of the women. Because prior studies have shown that the effects of periodontal disease vary depending on whether a person smokes, researchers examined the associations stratified by smoking status.

After a mean follow-up time of 6.7 years, 2,124 women were diagnosed with breast cancer. The researchers found that among all women, the risk of breast cancer was 14 percent higher in women who had periodontal disease.

Among women who had quit smoking within the past 20 years, those with periodontal disease had a 36 percent higher risk of breast cancer. Women who were smoking at the time of this study had a 32 percent higher risk if they had periodontal disease, but the association was not statistically significant. Those who had never smoked and had quit more than 20 years ago had a 6 percent and 8 percent increased risk, respectively, if they had periodontal disease.

“We know that the bacteria in the mouths of current and former smokers who quit recently are different from those in the mouths of non-smokers,” Freudenheim explained. One possible explanation for the link between periodontal disease and breast cancer is that those bacteria enter the body’s circulation and ultimately affect breast tissue. However, further studies are needed to establish a causal link, Freudenheim said.

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